{"id":3367,"date":"2021-08-01T00:37:00","date_gmt":"2021-07-31T22:37:00","guid":{"rendered":"https:\/\/cedkqn.med.uni-giessen.de\/?p=3367"},"modified":"2022-06-15T10:35:11","modified_gmt":"2022-06-15T08:35:11","slug":"running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease","status":"publish","type":"post","link":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/","title":{"rendered":"Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>ABSTRACT \u2013 Background and Aims:<\/strong>\u00a0Intensifying therapy for Paediatric Crohn\u2019s Disease (CD) by early use of immunomodulators and biologics has been proposed for cases in which predictors of poor outcome (POPO) were present. We investigated therapy stratifying potential comparing POPO-positive and -negative CD patients from CEDATA-GPGE\u00ae, a German-Austrian Registry for Paediatric Inflammatory Bowel disease.\u00a0<\/p>\n\n\n\n<p><strong>Methods:<\/strong>\u00a0CD patients (1-18 years) registered in CEDATA-GPGE\u00ae (2004-2018) within 3 months of diagnosis and at least two follow-up visits were included. Disease course and treatments over time were analysed regarding positivity of POPO criteria and test statistical properties.\u00a0<\/p>\n\n\n\n<p><strong>Results:<\/strong>\u00a0709\/1084 patients included had at least one POPO criterion (65.4%): 177 patients (16.3%) had persistent disease (POPO2), 581 (53.6%) extensive disease (POPO3), 21 (1.9%) severe growth retardation POPO4, 47 (4.3%) stricturing\/penetrating disease (POPO6) and 122 (11.3%) perianal disease (POPO7). Patients with persistent disease differed significantly in lack of sustained remission >1 year (Odd Ratio (OR) 1.49 [1.07-2.07],\u00a0<em>p<\/em>\u00a0= 0.02), patients with initial growth failure in growth failure at end of observation (OR 51.16 [19.89-131.62],\u00a0<em>p<\/em>\u00a0< 0.0001), patients with stricturing and penetrating disease as well as perianal disease in need for surgery (OR 17.76 [9.39-33.58],\u00a0<em>p<\/em>\u00a0< 0.001; OR 2.56 [1.58-4.15],\u00a0<em>p<\/em>\u00a0< 0.001, respectively). Positive Predictive Value for lack of sustained remission was >60% for patients with initial growth failure, persistent or stricturing\/penetrating disease.\u00a0<\/p>\n\n\n\n<p><strong>Conclusion:<\/strong>\u00a0Predictors of poor outcome with complicated courses of disease were common in CEDATA-GPGE\u00ae. An early intensified approach for paediatric CD patients with POPO-positivity (POPO2-4, 6-7) should be considered, because they have an increased risk to fare poorly.<\/p>\n\n\n\n<p>Weiterlesen: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8430211\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8430211\/\u00a0<\/a><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-fc4fd283 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link\" href=\"http:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2022\/02\/Running_behind_POPO_Impact_of_predictors_of_poor_outcome_for_treatment_stratification.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">DOWNLOAD<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>ABSTRACT \u2013 Background and Aims:\u00a0Intensifying therapy for Paediatric Crohn\u2019s Disease (CD) by early use of immunomodulators and biologics has been proposed for cases in which predictors of poor outcome (POPO) were present. We investigated therapy stratifying potential comparing POPO-positive and -negative CD patients from CEDATA-GPGE\u00ae, a German-Austrian Registry for Paediatric Inflammatory Bowel disease.\u00a0 Methods:\u00a0CD patients &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"\" href=\"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/\"> <span class=\"screen-reader-text\">Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease<\/span> Weiterlesen &raquo;<\/a><\/p>\n","protected":false},"author":1,"featured_media":3412,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","footnotes":""},"categories":[3],"tags":[25,15,22,21],"class_list":["post-3367","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-presse","tag-crohns-disease","tag-pediatric-patients","tag-predictors","tag-predictors-of-poor-outcome"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease - CEDKQN<\/title>\n<meta name=\"description\" content=\"CEDKQN Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease - CEDKQN\" \/>\n<meta property=\"og:description\" content=\"CEDKQN Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"CEDKQN\" \/>\n<meta property=\"article:published_time\" content=\"2021-07-31T22:37:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-06-15T08:35:11+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2021\/08\/Running-behind-popo.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1232\" \/>\n\t<meta property=\"og:image:height\" content=\"300\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"cedkqnadmin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Geschrieben von\" \/>\n\t<meta name=\"twitter:data1\" content=\"cedkqnadmin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data2\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/\"},\"author\":{\"name\":\"cedkqnadmin\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#\\\/schema\\\/person\\\/6b639406f808d178d5d1eea15d2b77c3\"},\"headline\":\"Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease\",\"datePublished\":\"2021-07-31T22:37:00+00:00\",\"dateModified\":\"2022-06-15T08:35:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/\"},\"wordCount\":283,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/wp-content\\\/uploads\\\/2021\\\/08\\\/Running-behind-popo.jpg\",\"keywords\":[\"Crohn&#039;s disease\",\"pediatric patients\",\"predictors\",\"predictors of poor outcome\"],\"articleSection\":[\"Presse\"],\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/\",\"url\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/\",\"name\":\"Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease - CEDKQN\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/wp-content\\\/uploads\\\/2021\\\/08\\\/Running-behind-popo.jpg\",\"datePublished\":\"2021-07-31T22:37:00+00:00\",\"dateModified\":\"2022-06-15T08:35:11+00:00\",\"description\":\"CEDKQN Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/#breadcrumb\"},\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/#primaryimage\",\"url\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/wp-content\\\/uploads\\\/2021\\\/08\\\/Running-behind-popo.jpg\",\"contentUrl\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/wp-content\\\/uploads\\\/2021\\\/08\\\/Running-behind-popo.jpg\",\"width\":1232,\"height\":300},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2021\\\/08\\\/01\\\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Startseite\",\"item\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#website\",\"url\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/\",\"name\":\"CEDKQN\",\"description\":\"Eine weitere WordPress-Website\",\"publisher\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"de\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#organization\",\"name\":\"CEDKQN\",\"url\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/wp-content\\\/uploads\\\/2020\\\/08\\\/Logo-01-v02-Transp.png\",\"contentUrl\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/wp-content\\\/uploads\\\/2020\\\/08\\\/Logo-01-v02-Transp.png\",\"width\":2000,\"height\":2000,\"caption\":\"CEDKQN\"},\"image\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#\\\/schema\\\/person\\\/6b639406f808d178d5d1eea15d2b77c3\",\"name\":\"cedkqnadmin\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ad26f2e1cda0294036e6df10b5c6f5836d93c4f8329ac6288ad5e253dceb6f6f?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ad26f2e1cda0294036e6df10b5c6f5836d93c4f8329ac6288ad5e253dceb6f6f?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ad26f2e1cda0294036e6df10b5c6f5836d93c4f8329ac6288ad5e253dceb6f6f?s=96&d=mm&r=g\",\"caption\":\"cedkqnadmin\"},\"url\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/author\\\/cedkqnadmin\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease - CEDKQN","description":"CEDKQN Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease","robots":{"index":"noindex","follow":"follow"},"og_locale":"de_DE","og_type":"article","og_title":"Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease - CEDKQN","og_description":"CEDKQN Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease","og_url":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/","og_site_name":"CEDKQN","article_published_time":"2021-07-31T22:37:00+00:00","article_modified_time":"2022-06-15T08:35:11+00:00","og_image":[{"width":1232,"height":300,"url":"http:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2021\/08\/Running-behind-popo.jpg","type":"image\/jpeg"}],"author":"cedkqnadmin","twitter_card":"summary_large_image","twitter_misc":{"Geschrieben von":"cedkqnadmin","Gesch\u00e4tzte Lesezeit":"2\u00a0Minuten"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/#article","isPartOf":{"@id":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/"},"author":{"name":"cedkqnadmin","@id":"https:\/\/cedkqn.med.uni-giessen.de\/#\/schema\/person\/6b639406f808d178d5d1eea15d2b77c3"},"headline":"Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease","datePublished":"2021-07-31T22:37:00+00:00","dateModified":"2022-06-15T08:35:11+00:00","mainEntityOfPage":{"@id":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/"},"wordCount":283,"commentCount":0,"publisher":{"@id":"https:\/\/cedkqn.med.uni-giessen.de\/#organization"},"image":{"@id":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/#primaryimage"},"thumbnailUrl":"https:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2021\/08\/Running-behind-popo.jpg","keywords":["Crohn&#039;s disease","pediatric patients","predictors","predictors of poor outcome"],"articleSection":["Presse"],"inLanguage":"de","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/","url":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/","name":"Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease - CEDKQN","isPartOf":{"@id":"https:\/\/cedkqn.med.uni-giessen.de\/#website"},"primaryImageOfPage":{"@id":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/#primaryimage"},"image":{"@id":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/#primaryimage"},"thumbnailUrl":"https:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2021\/08\/Running-behind-popo.jpg","datePublished":"2021-07-31T22:37:00+00:00","dateModified":"2022-06-15T08:35:11+00:00","description":"CEDKQN Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease","breadcrumb":{"@id":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/#breadcrumb"},"inLanguage":"de","potentialAction":[{"@type":"ReadAction","target":["https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/"]}]},{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/#primaryimage","url":"https:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2021\/08\/Running-behind-popo.jpg","contentUrl":"https:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2021\/08\/Running-behind-popo.jpg","width":1232,"height":300},{"@type":"BreadcrumbList","@id":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2021\/08\/01\/running-behind-popo-impact-of-predictors-of-poor-outcome-for-treatment-stratification-in-pediatric-crohns-disease\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Startseite","item":"https:\/\/cedkqn.med.uni-giessen.de\/"},{"@type":"ListItem","position":2,"name":"Running Behind \u201ePOPO\u201c \u2013 Impact of Predictors of Poor Outcome for Treatment Stratification in Pediatric Crohn\u2019s Disease"}]},{"@type":"WebSite","@id":"https:\/\/cedkqn.med.uni-giessen.de\/#website","url":"https:\/\/cedkqn.med.uni-giessen.de\/","name":"CEDKQN","description":"Eine weitere WordPress-Website","publisher":{"@id":"https:\/\/cedkqn.med.uni-giessen.de\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/cedkqn.med.uni-giessen.de\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"de"},{"@type":"Organization","@id":"https:\/\/cedkqn.med.uni-giessen.de\/#organization","name":"CEDKQN","url":"https:\/\/cedkqn.med.uni-giessen.de\/","logo":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/cedkqn.med.uni-giessen.de\/#\/schema\/logo\/image\/","url":"https:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2020\/08\/Logo-01-v02-Transp.png","contentUrl":"https:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2020\/08\/Logo-01-v02-Transp.png","width":2000,"height":2000,"caption":"CEDKQN"},"image":{"@id":"https:\/\/cedkqn.med.uni-giessen.de\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/cedkqn.med.uni-giessen.de\/#\/schema\/person\/6b639406f808d178d5d1eea15d2b77c3","name":"cedkqnadmin","image":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/secure.gravatar.com\/avatar\/ad26f2e1cda0294036e6df10b5c6f5836d93c4f8329ac6288ad5e253dceb6f6f?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/ad26f2e1cda0294036e6df10b5c6f5836d93c4f8329ac6288ad5e253dceb6f6f?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/ad26f2e1cda0294036e6df10b5c6f5836d93c4f8329ac6288ad5e253dceb6f6f?s=96&d=mm&r=g","caption":"cedkqnadmin"},"url":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/author\/cedkqnadmin\/"}]}},"_links":{"self":[{"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/posts\/3367","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/comments?post=3367"}],"version-history":[{"count":8,"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/posts\/3367\/revisions"}],"predecessor-version":[{"id":3461,"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/posts\/3367\/revisions\/3461"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/media\/3412"}],"wp:attachment":[{"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/media?parent=3367"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/categories?post=3367"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/wp-json\/wp\/v2\/tags?post=3367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}