{"id":3434,"date":"2017-12-05T12:01:00","date_gmt":"2017-12-05T11:01:00","guid":{"rendered":"https:\/\/cedkqn.med.uni-giessen.de\/?p=3434"},"modified":"2022-06-15T10:40:19","modified_gmt":"2022-06-15T08:40:19","slug":"prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge","status":"publish","type":"post","link":"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2017\/12\/05\/prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge\/","title":{"rendered":"Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE"},"content":{"rendered":"\n<p>Abstract<\/p>\n\n\n\n<p><strong>Aim:&nbsp;<\/strong>To determine the prevalence of anemia and its association with disease severity in children and adolescents with IBD.<\/p>\n\n\n\n<p><strong>Methods:&nbsp;<\/strong>CEDATA-GPGE is a registry for pediatric patients with IBD in Germany and Austria from 90 specialized centers. As markers of disease severity, analysis included patient self-assessment on a Likert scale (1-5; 1 = very good) and physicians&#8216; general assessment (0 = no activity to 4 = severe disease) and the disease indices. Anemia was defined as hemoglobin concentration below the 3rd percentile.<\/p>\n\n\n\n<p><strong>Results:&nbsp;<\/strong>Prevalence of anemia was 65.2% in CD and 60.2% in UC. Anemic CD and UC patients showed significantly worse self-assessment than patients without anemia (average \u00b1 standard deviation; CD: 3.0 \u00b1 0.9 versus 2.5 \u00b1 0.9,&nbsp;<em>p<\/em>&nbsp;&lt; 0.0001; UC: 2.9 \u00b1 0.9 versus 2.3 \u00b1 0.9,&nbsp;<em>p<\/em>&nbsp;&lt; 0.0001). Accordingly, physicians&#8216; general assessment (PGA) was significantly worse in anemic than in nonanemic patients in CD (<em>p<\/em>&nbsp;&lt; 0.0001) and UC (<em>p<\/em>&nbsp;&lt; 0.0001). PCDAI in anemic CD,&nbsp;<em>p<\/em>&nbsp;&lt; 0.0001, and PUCAI in anemic UC patients,&nbsp;<em>p<\/em>&nbsp;&lt; 0.0001, were significantly higher than in nonanemic patients. 40.0% of anemic CD and 47.8% of anemic UC patients received iron during follow-up.<\/p>\n\n\n\n<p><strong>Conclusion:&nbsp;<\/strong>Almost 2\/3 of pediatric IBD patients are anemic. Patients&#8216; self-assessment and disease severity as determined by PGA and activity indices are worse in anemic patients. Contrastingly, only a minority received iron therapy.<\/p>\n\n\n\n<p>Weiterlesen: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5735663\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5735663\/<\/a><\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link\" href=\"http:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2022\/02\/Prevalence_of_Anemia_in_Pediatric_IBD_Patients_and_Impact_on_Disease_Severity.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">DOWNLOAD<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Abstract Aim:&nbsp;To determine the prevalence of anemia and its association with disease severity in children and adolescents with IBD. Methods:&nbsp;CEDATA-GPGE is a registry for pediatric patients with IBD in Germany and Austria from 90 specialized centers. As markers of disease severity, analysis included patient self-assessment on a Likert scale (1-5; 1 = very good) and &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"\" href=\"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2017\/12\/05\/prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge\/\"> <span class=\"screen-reader-text\">Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE<\/span> Weiterlesen &raquo;<\/a><\/p>\n","protected":false},"author":13,"featured_media":3401,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-global-header-display":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","footnotes":""},"categories":[3],"tags":[24,33,32],"class_list":["post-3434","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-presse","tag-cedata-gpge","tag-ibd-registry","tag-prevalence-of-anemia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE - CEDKQN<\/title>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE - CEDKQN\" \/>\n<meta property=\"og:description\" content=\"Abstract Aim:&nbsp;To determine the prevalence of anemia and its association with disease severity in children and adolescents with IBD. Methods:&nbsp;CEDATA-GPGE is a registry for pediatric patients with IBD in Germany and Austria from 90 specialized centers. As markers of disease severity, analysis included patient self-assessment on a Likert scale (1-5; 1 = very good) and &hellip; Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE Weiterlesen &raquo;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cedkqn.med.uni-giessen.de\/index.php\/2017\/12\/05\/prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge\/\" \/>\n<meta property=\"og:site_name\" content=\"CEDKQN\" \/>\n<meta property=\"article:published_time\" content=\"2017-12-05T11:01:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-06-15T08:40:19+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/cedkqn.med.uni-giessen.de\/wp-content\/uploads\/2022\/02\/Prevalence-of-Anemia.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1232\" \/>\n\t<meta property=\"og:image:height\" content=\"300\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Laura Eckes\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Geschrieben von\" \/>\n\t<meta name=\"twitter:data1\" content=\"Laura Eckes\" \/>\n\t<meta name=\"twitter:label2\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data2\" content=\"2\u00a0Minuten\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2017\\\/12\\\/05\\\/prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2017\\\/12\\\/05\\\/prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge\\\/\"},\"author\":{\"name\":\"Laura Eckes\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#\\\/schema\\\/person\\\/68731aaa8c70de3b8bfaadd6889e16be\"},\"headline\":\"Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE\",\"datePublished\":\"2017-12-05T11:01:00+00:00\",\"dateModified\":\"2022-06-15T08:40:19+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2017\\\/12\\\/05\\\/prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge\\\/\"},\"wordCount\":240,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2017\\\/12\\\/05\\\/prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/wp-content\\\/uploads\\\/2022\\\/02\\\/Prevalence-of-Anemia.jpg\",\"keywords\":[\"CEDATA-GPGE\",\"IBD-Registry\",\"Prevalence of Anemia\"],\"articleSection\":[\"Presse\"],\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2017\\\/12\\\/05\\\/prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2017\\\/12\\\/05\\\/prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge\\\/\",\"url\":\"https:\\\/\\\/cedkqn.med.uni-giessen.de\\\/index.php\\\/2017\\\/12\\\/05\\\/prevalence-of-anemia-in-pediatric-ibd-patients-and-impact-on-disease-severity-results-of-the-pediatric-ibd-registry-cedata-gpge\\\/\",\"name\":\"Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE - 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